6 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... #Acute #Chronic ... #Cirrhosis #Hepatology ... #gastroenterology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Differential Diagnosis ... • NAFLD • Cirrhosis ... • Chronic Viral ... Hepatopathy • Acute ... Diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 20x normal - Acute ... 5-10x normal - Chronic ... #Injury #hepatology ... #differential # ... diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALF): • Liver ... : < 1 • Cirrhosis ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Diagnosis Algorithm ... #injury #hepatitis ... diagnosis #algorithm ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
presentation • Chronic ... - ongoing ↑ LFTs ... #differential # ... #algorithm #gastroenterology ... #hepatology