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diagnosis liver chemistry drug function hepatitis hepatocellular idiosyncratic induced interpretation management rvalue tests
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
) - Differential ... (>1000): • DILI ... Drug-induced liver injury ... Diagnosis #hepatology ... #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential ... #Differential # ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Unconjugated Bili ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
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