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diagnosis causes acute lfts dili management transaminitis aclf chronic cirrhosis druginduced failure function hepatocellular hepatomegaly idiosyncratic induced liverenzymes liverinjury severe
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Injury - Ichemic ... obstruction - Drug-Induced ... liver injury ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... #differential # ... #algorithm #gastroenterology ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... Chronic Viral Hepatitis ... 1000): • DILI (Drug-induced ... liver injury) ... #Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... valproate, azoles), Drugs ... #Injury #Differential
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... , Recreational Drugs ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis Algorithm ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
(AAH) Drug-Induced ... Liver Injury (DILI ... ) Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... • Drug Induced ... #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... #injury #hepatitis ... #hepatology
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