20 results
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern

- Dr. Eric Strong @DrEricStrong

#Jaundice #Workup
An Approach to Jaundice ... Workup Algorithm by CBC ... and LFT Pattern ... DrEricStrong #Jaundice ... #Diagnosis #Hepatology
Summary table of comparison of the difference between primary biliary cholangitis (PBC) and primary sclerosing cholangitis
between primary biliary ... cholangitis (PBC ... sclerosing cholangitis (PSC ... #differential #hepatology ... #gastroenterology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... discomfort Signs: Jaundice ... #PBC #Primary ... #Biliary #Cirrhosis ... Diagnosis #Algorithm #hepatology
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
Causes of Biliary ... pancreatitis, PSC ... #Dilatation #causes ... differential #diagnosis #hepatology ... #gastroenterology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... intralobular bile ducts causes ... hyperpigmentation • Jaundice ... No extrahepatic biliary ... diagnosis #workup #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... - CBD stone, Biliary ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... on Ultrasound Biliary ... Gallstones • Biliary ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Bile Ducts • PSC ... Duct Stone • Biliary ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... hepatitis, Acute biliary ... Malignancy, 1° PBC ... Extrahepatic • Biliary ... Acute #algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... Drugs - Primary biliary ... Cholangitis (PBC ... - Other biliary ... Diagnosis #Algorithm #hepatology