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diagnosis differential algorithm hematology management causes cirrhosis pathophysiology lfts hepatic comparison hepatitis treatment disease gastroenterology injury table workup anemia laboratory
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of hemolysis or liver ... breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... Congenital #bilirubin #hepatology
Algorithm and Differential Diagnosis of Hyperbilirubinemia Direct = Conjugated Indirect = Unconjugated #Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Hyperbilirubinemia Direct = Conjugated ... Indirect = Unconjugated ... #Diagnosis #Jaundice ... Direct #Indirect #Conjugated ... #Unconjugated #
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Pathophysiology • Conjugated ... Bilirubin • Unconjugated ... Pathophysiology #hepatology ... #Liver
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Jaundice Evaluation ... Management #EM #IM #GI #Jaundice ... Direct #Indirect #Conjugated ... #Unconjugated #
Causes of Jaundice - Prehepatic, Intrahepatic, Extrahepatic #Diagnosis #Differential #Jaundice #Prehepatic #Intrahepatic #Extrahepatic #Unconjugated #Conjugated ** GrepMed Recommended
Causes of Jaundice ... #Differential #Jaundice ... #Extrahepatic #Unconjugated ... #Conjugated
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Pre-Hepatic - Unconjugated ... II) Hepatic - Conjugated ... Cholangitis #Jaundice ... Algorithm #Causes #Hepatology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... drug reactions) Conjugated ... postoperative jaundice ... neoplasms #Jaundice ... Classification #diagnosis #conjugated
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
Liver Function Tests ... Bilirubin - Unconjugated ... Indirect) - Conjugated ... Prothrombin #Liver
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
→ Biliverdin → Unconjugated ... Conjugation → Conjugated ... common bile duct Unconjugated ... bilirubin, and conjugated ... pathophysiology #hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Approach to Conjugated ... elevation + >20% conjugated ... MRCP, ERCP, liver ... MatthewHoMD #Conjugated ... gastroenterology #hepatology
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