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diagnosis differential hepatology pediatrics peds unconjugated algorithm bhutani causes neonatal nomogram risk stratification thresholds congenital ddxof direct indirect inherited neurotoxicity
Algorithm and Differential Diagnosis of Hyperbilirubinemia Direct = Conjugated Indirect = Unconjugated #Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Differential Diagnosis of Hyperbilirubinemia ... Direct = Conjugated ... #Diagnosis #Jaundice ... #Hyperbilirubinemia ... Direct #Indirect #Conjugated
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Jaundice Evaluation ... Algorithm #Diagnosis #Management ... #EM #IM #GI #Jaundice ... #Hyperbilirubinemia ... Direct #Indirect #Conjugated
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... Unconjugated hyperbilirubinemia ... drug reactions) Conjugated ... hyperbilirubinemia ... postoperative jaundice
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Hyperbilirubinemia ... II) Hepatic - Conjugated ... Hyperbilirubinemia ... Cholangitis #Jaundice
Jaundice - Pathophysiology and Causes - Amy Chung, MD, MSc @AmyChung #Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... Amy Chung, MD, MSc ... @AmyChung #Jaundice ... #Pathophysiology ... #Differential #Unconjugated
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
hyperbilirubinemia ... breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... • Increase in conjugated
Inherited forms of Hyperbilirubinemia Major pathways involved in bilirubin production, conjugation, and excretion. Notes: Both the UB
Inherited forms of Hyperbilirubinemia ... Decreased MRP2 - Conjugated ... Decreased OATP1B - Conjugated ... Inherited #forms #Hyperbilirubinemia ... #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... (DIC, ascites, jaundice ... Intrahepatic Cholestasis Management ... obgyn #diagnosis #management ... #pathophysiology
Threshold for Initiating Exchange Transfusion by Risk Stratum. Bhutani et al. Pediatrics. 1999. #Peds #Pediatrics #Diagnosis #Management
Pediatrics #Diagnosis #Management ... #Neonatal #Jaundice ... #Hyperbilirubinemia
Assess risk for developing subsequent neurotoxicity. This will tell you: a) phototherapy or b) exchange transfusion #Peds #Pediatrics
Pediatrics #Diagnosis #Management ... #Neonatal #Jaundice ... #Hyperbilirubinemia
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