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Clinical Examination for Liver and Biliary Diseases
1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Clinical Examination ... erythema 2) Face: Jaundice ... Xanthelasma and jaundiced ... disease #signs #diagnosis
Clinical Features and Complications of β-thalassaemia Major
 - Pallor
 - Jaundice
 - Bossing of the skull
Clinical Features ... - Pallor - Jaundice ... Signs #Symptoms #Diagnosis
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... Hepatitis - Onset of jaundice ... before the onset of jaundice ... days of onset of jaundice ... Autoimmune #Hepatitis #Diagnosis
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... ) • Onset of jaundice ... before the onset of jaundice ... days of onset of jaundice ... #diagnosis #Alcoholic
Clinical Signs of Pancreatic Cancer
Jaundice
Cachexia
Depression
Vomiting from duodenal obstruction
Lymphadenopathy
Palpable gallbladder (Courvoisier's sign)
Hepatomegaly (extrahepatic biliary obstruction/secondary deposits)
Scratch marks
Clinical Signs of ... Pancreatic Cancer Jaundice ... marks (obstructive jaundice ... Cancer #Signs #diagnosis
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Weil's Disease: Jaundice ... disease ARDS Diagnosis ... Epidemiologic exposure + clinical ... #microbiology #diagnosis
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... on clinical examination ... bilirubin #hepatology #diagnosis
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Lutzomyia verrucarum Clinical ... hemolytic anemia, jaundice ... toxo reactivation Clinical ... Nodular → Mular DIAGNOSIS ... #Oroya #Fever #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... Pruritus, Mild jaundice ... post-partum • Typical clinical ... post-partum • Typical clinical ... #differential #diagnosis
Jaundice Differential Diagnosis: A short guide

By Dr. Khudhur Mohammed @khudhur_moh

#jaundice #gastroenterology #algorithm #differential #diagnosis #hyperbilirubinemia #bilirubin
Jaundice Differential ... Diagnosis: A short ... khudhur_moh #jaundice ... #differential #diagnosis