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Hepatitis B Management in Cancer

DOI: 10.1200/JCO.20.01757

#HepatitisB #HBV #HepBV #Management #Cancer #oncology #hepatology #algorithm
Hepatitis B Management ... in Cancer DOI: ... JCO.20.01757 #HepatitisB ... #Cancer #oncology ... #hepatology #algorithm
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Injury - Ichemic hepatitis ... - Wilson disease ... Severe #Acute #Causes ... #Differential #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Syndrome, Celiac Disease ... Pancreatic Pseudocyst, Cancer ... Differential #Diagnosis #Causes ... Acute #algorithm #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
diagnosis of Alcoholic Hepatitis ... ) • Onset of jaundice ... metabolic liver disease ... (Wilson disease ... #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
of Autoimmune Hepatitis ... - Onset of jaundice ... metabolic liver disease ... (Wilson disease ... #Diagnosis #Hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... 15 percent) - Hepatitis ... - Wilson disease ... #Differential #Hepatology ... #Cirrhosis #Causes
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hemochromatosis • Wilson's Disease ... Infectious • Hepatitis ... • Alcoholic Hepatitis ... Diagnosis #Algorithm #Causes ... #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
underlying liver disease ... (DILI) Viral Hepatitis ... Procedures Management ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... onset RUQ pain, jaundice ... #SickleCell #Disease ... Hepatobiliary #hepatology ... #hepatitis #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Cholestatic disease ... • Alcoholic hepatitis ... • Pancreatic cancer ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes