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diagnosis differential management algorithm causes treatment disease lfts transaminitis ascites injury pathophysiology syndrome comparison gastroenterology hematology physicalexam signs acute albumin
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
/Liver failure ... hyperpigmentation • Jaundice ... or higher • Liver ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Nonalcoholic fatty liver ... #Differential #Hepatology
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 Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... Alcohol-Associated Hepatitis ... (DILI) Viral Hepatitis ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... • NAFLD • Cirrhosis ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... Differential #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... , Toxic Hepatitis ... CMV), Alcoholic cirrhosis ... #Patterns #Liver ... #Injury #hepatology
Signs of Chronic Liver Disease ( Cirrhosis ) #Diagnosis #Cirrhosis #Signs #Symptoms #Hepatology
Signs of Chronic Liver ... Disease ( Cirrhosis ... #Diagnosis #Cirrhosis ... Signs #Symptoms #Hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
diagnosis of Alcoholic Hepatitis ... ) • Onset of jaundice ... ) or metabolic liver ... Possible drug-induced liver ... #AH #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... Infectious • Hepatitis ... • Alcoholic Hepatitis ... Primary Biliary Cirrhosis ... Algorithm #Causes #Hepatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
of Autoimmune Hepatitis ... - Onset of jaundice ... ) or metabolic liver ... Possible drug-induced liver ... #Diagnosis #Hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Diagnosis Chronic liver ... disease (cirrhosis ... or chronic hepatitis ... failure - 3-5% Cirrhosis ... Differential #Diagnosis #hepatology
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