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diagnosis differential hematology algorithm aptt gastroenterology prolonged pt treatment ascites biliary bilirubin bleeding bruising chemistry cholangitis classification congenital dic disseminated
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... Normal Peritoneum ... Liver disease ... - Cirrhosis ... #differential #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... /Liver failure ... hyperpigmentation • Jaundice ... malignancies, Hepatic ... diagnosis #workup #hepatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Jcortesizaguirr #Abnormal ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... • Reduced liver ... amyloidosis #Abnormal ... #differential #hematology ... #coagulation
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
<45% and SF is normal ... Patients with cirrhosis ... hemochromatosis; HIC, hepatic ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
- If both are normal ... • Albumin • Coagulation ... replaced by non-hepatic ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... Acquired: • Heparin ... intravascular coagulation ... discern these causes ... Differential #Diagnosis #Hematology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
Hepatic Encephalopathy ... Diagnosis and Management ... by liver insufficiency ... Prevalence: At cirrhosis ... #treatment #hepatology
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