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diagnosis hematology differential management oncology acidosis acute aplastic classification elevation gap globulin hemeonc hemophagocytic hiv hlh hypogammaglobulinemia immunodeficiency immunology lactate
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases and hepatitis ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... : - Hepatitis ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Most common cytopenia ... Out Secondary Causes ... factor (GCSF) treatments ... #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... #hematology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
infection - Most common ... 14%), in which case ... enzymes ↑ • Mild anemia ... infection • Viral hepatitis ... antibody test) Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Diagnosis The most common ... / hypoxemia -> focus ... before beginning treatment ... - Compartment syndrome ... 30mmHg) - Severe anemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... HBV, EBV, VZV, hepatitis ... PBC, PSC, Viral hepatitis ... Thalassemia, Sickle cell anemia ... Comment on type
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... Acquired) HLH: - Common ... Presentation • Common ... - Cytopenias (anemia ... Diagnosis #Management #Hematology
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