117 results
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... and Causes - ... #Pathophysiology ... #Differential # ... Unconjugated #Causes
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... postoperative jaundice ... miscellaneous causes ... #unconjugated #differential ... #causes
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... #Differential # ... Diagnosis #Algorithm #Causes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... and hepatorenal syndrome ... • Budd Chiari syndrome ... sarcoidosis) • Liver ... #Diagnosis #causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... (DIC, ascites, jaundice ... infiltration) Differential ... diagnosis #management #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Pancreatitis - Elevated Liver ... - Budd Chiari Syndrome ... Complications #pathophysiology ... #signs #symptoms
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential ... - Refeeding Syndrome ... #Hypokalemia #Differential ... potassium #low #pathophysiology
Abnormal Lipid Profiles - Differential Diagnosis Algorithm

Increased Cholesterol and Triglycerides 
 - Genetic Causes
Lipid Profiles - Differential ... • Nephrotic Syndrome ... • Obstructive Liver ... • Nephrotic Syndrome ... LipidProfiles #Differential
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... obstruction, HELLP Syndrome ... #Injury #Differential ... #Diagnosis #Causes
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Virilization - Differential ... • Cushing's Syndrome ... • Obesity • Liver ... #Virilization #Differential ... endocrinology #causes