73 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... (DIC, ascites, jaundice ... Findings: • ↑AST/ALT ... #pathophysiology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... discomfort Signs: Jaundice ... Associated history: Symptoms ... Elevated ALP 2. ... Liver biopsy findings
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... PBC Signs and Symptoms ... hyperpigmentation • Jaundice ... or higher • Liver
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... - Symptoms of ... hepatocellular pattern of liver ... Hepatitis (eg Viral) Management ... AIH #Diagnosis #Management
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... cycle found in the liver ... Clinical presentation also ... includes symptoms ... Toxicology #Diagnosis #Management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
: INR/PT, aPTT(liver ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... bypass), LFT (liver ... not required in all
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
suspected HH based on symptoms ... Step 3: All patients ... also be considered ... ALT, alanine aminotransferase ... algorithm #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... (for secondary APS ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Aphasia - Pathophysiology and Clinical Findings
Broca's Aphasia - Expressive language impairment: non-Fluent
 - Sensory speech areas
Aphasia - Pathophysiology ... motor areas is also ... nearby areas is also ... diagnosis #signs #symptoms ... Brocas #Wernickes #neurology