11 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... Prunelle Getten #AdultOnset ... diagnosis #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... , CRP, AST+ALT, ... BrighamChiefs #AdultOnset ... #AOSD #rheumatology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... calcification appears as ... 12-24 Hours • Fever ... #Gout #Comparison ... #rheumatology #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... - Pel-Ebstein fever ... body, but can also ... #NonHodgkins #comparison ... #differential #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... +, Adult-onset Still ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Insect stings Disease ... symptoms - Headache, fever ... doi: 10.1111/all ... Urticaria #diagnosis #rheumatology ... #comparison #table
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... - Nonremitting fever ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... to repair DNA, as ... aplastic anemia Treatment ... Anemia #oncology #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
calcification appears as ... Acute Pseudogout: Treatment ... it may present as ... acute neck pain, fever ... Deposition #Disease #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Mycoplasma, EBV ... Disorders Such As ... Symptoms: High fevers ... , chills, flank ... hemolytic #anemia #hematology