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management leukemia anesthesia anesthesiology checklist chronic comparison druginduced hodgkins intraoperative lupus lymphocytic lymphoma mgus monoclonal rheumatology signs algorithm anaesthetic cancer
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... • Age: 60-80 Clonal ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
1 or more: • Clonal ... serum free light chain ... of MM), light chain ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Diagnosis: • ... #workup #oncology ... #hematology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... disease 48% (light chain ... - Clonal bone marrow ... cell in bone marrow ... #Management #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
constitutional symptoms ... type) < 3 g/dL • Clonal ... to the plasma cell ... proliferative disorder • Clonal ... #diagnosis #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... cytometry → >500/uL clonal ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
• CNS symptoms ... Thick and thin smear ... node biopsy • Clinical ... values supporting hematologic ... #diagnosis
High Central Neuraxial Block - Guidelines for Crises in Anaesthesia • Can occur with deliberate or accidental
Central Neuraxial Block ... hypnosis as soon as clinical ... • Chin lift ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia Signs of severe toxicity: • Sudden alteration in
without tonic-clonic ... bradycardia, conduction blocks ... inform immediate clinical ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
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