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diagnosis management rheumatology signs workup algorithm anemia chronic classification differential disease disorders hodgkins lymphocytic lymphoproliferative pathophysiology syndrome agglutinin alkpos anaplastic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... • Age: 60-80 Clonal ... (SLL) CLL Symptoms ... lymphoma #Leukemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... leukemia #CLL ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... involved) • No leukemic ... • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
cytometry → >500/uL clonal ... immunophenotype Clinical ... lymphoma (Richter ... uw_IMresidency #CLL ... #oncology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... common - T Cell ... ~10% - B-Cell ... Treated Like Acute Leukemias ... pathophysiology #Hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
PTLD) Definition: Lymphoid ... hematopoietic cell ... Epidemiology: Lymphoma ... , unexplained hematologic ... Lymphoproliferative #Disorders #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... - Clinical Presentation ... ingestion • B symptoms ... classification #hematology ... #oncology #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... development of skin symptoms ... (malignancy), lymphoma ... , breast CA - Hematologic ... #oncology
Anaplastic large cell lymphoma, ALK+ Clinical • First 3 decades of life, M>F • Often nodal +
lymphoma, ALK+ ... Clinical • First ... variant can have leukemic ... advanced stage + B symptoms ... Anaplastic #largecell #lymphoma
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
autoimmune disorder or lymphoid ... malignancy (CLL ... - Monoclonal - Lymphoid ... Viral Infection Clinical ... hemolytic #anemia #hematology
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