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diagnosis management lupus algorithm chronic classification comparison differential druginduced hodgkins lymphocytic lymphoma sle anemia aplastic cancer cell dequervains dil disorders
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... ALL Symptoms: ... • Age: 60-80 Clonal ... ) CLL Symptoms: ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... • Most common leukemia ... cytometry → >500/uL clonal ... immunophenotype Clinical ... #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... involved) • No leukemic ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... ~10% - B-Cell ... Treated Like Acute Leukemias ... Amy Chung, MD, MSc ... pathophysiology #Hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
When to look for clonal ... ) - Clinical symptoms ... Cytopenia, Other cell ... Diagnosis #Signs #Hematology ... #Workup
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
constitutional symptoms ... type) < 3 g/dL • Clonal ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... Constitutional symptoms ... • Immunologic Workup ... comparison #table #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Eichhoff's Test in de Quervain's Tenosynovitis 1) Patient makes a fist with fingers wrapped around the thumb 2)
reproduction of patient's symptoms ... abductor pollicis longus ... Tenosynovitis #clinical ... physicalexam #sports #msk ... #orthopedics #rheumatology
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