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diagnosis management algorithm chronic classification cll hodgkins lymphocytic lymphoma signs anemia aplastic approach arthritis behcet cancer cell comparison dequervains disease
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... • Age: 60-80 Clonal ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... cytometry → >500/uL clonal ... immunophenotype Clinical ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Orange or Hep C Clinical ... with no early symptoms ... #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... involved) • No leukemic ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... Amy Chung, MD, MSc ... pathophysiology #Hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
When to look for clonal ... ) - Clinical symptoms ... Diagnosis #Signs #Hematology ... #Workup
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Eichhoff's Test in de Quervain's Tenosynovitis 1) Patient makes a fist with fingers wrapped around the thumb 2)
reproduction of patient's symptoms ... abductor pollicis longus ... Tenosynovitis #clinical ... physicalexam #sports #msk ... #orthopedics #rheumatology
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 Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... virus (EBV) • Leukemia ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... Behcet disease) Differential ... tears, Ischemia, Leukemia ... #rheumatology #
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