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diagnosis leukemia chronic comparison hodgkins lymphoma management algorithm cancer classification cold differential gammopathy hemeonc heon hypereosinophilia mds mgus monoclonal myelodysplasia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Age: 60-80 Clonal ... CLL Symptoms: • ... Leukemia (CLL) ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... CLL Labs: 1. ... Leukemia #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... cytometry → >500/uL clonal ... immunophenotype Clinical ... Transformation to large cell ... uw_IMresidency #CLL
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
typically of B-cell ... Reed Sternberg cell ... based on: - Cell ... type (B cell, T ... NonHodgkins #comparison #oncology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
When to look for clonal ... ) - Clinical symptoms ... Cytopenia, Other cell ... Diagnosis #Signs #Hematology ... #Workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
constitutional symptoms ... type) < 3 g/dL • Clonal ... to the plasma cell ... proliferative disorder • Clonal ... #diagnosis #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
life Causes and clinical ... and duration of symptoms ... angioedema Other symptoms ... histology - Mast cell ... infiltration (lymphocytes
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • Plasma cell neoplasms ... MM, the plasma cell ... #Solitary #Cell ... #Hematology
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