16 results
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Incidence, Symptoms ... Toxicity #Toxicities #SideEffects ... #Table #Diagnosis ... #Pharmacology # ... Oncology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
of iniurv • Conus ... causing injury to conus ... Injury #Syndromes #diagnosis ... #pathophysiology ... #signs #symptoms
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... cytometry → >500/uL clonal ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... hematology #hemeonc #diagnosis
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Extrapyramidal Symptoms ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology # ... diagnosis #psychiatry
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... opacities • Diagnosis ... : >3 symptoms, or ... • Differential Diagnosis ... management #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... • Age: 60-80 Clonal ... Leukemia #Hematology #Oncology ... #Diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
constitutional symptoms ... type) < 3 g/dL • Clonal ... proliferative disorder • Clonal ... Significance #hematology #diagnosis ... #oncology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Jaw Jerk reflex, Clonus ... fasciculations Common Symptoms ... Medical time to diagnosis ... Other possible diagnosis