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diagnosis hematology chronic classification hodgkins lymphocytic management algorithm alkpos anaplastic associations cancers comparison dehydrogenase dermatology disorders elevated erythematosus hemeonc hemepath
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... • Age: 60-80 Clonal ... (SLL) CLL Symptoms ... lymphoma #Leukemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... aplasia • ITP ... cell leukemia ... leukemia #CLL ... diagnosis #workup #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- B symptoms ... involved) • No leukemic ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... • Most common leukemia ... cytometry → >500/uL clonal ... lymphoma (Richter ... #oncology #hematology
Infection-Related Cancers Viruses: • HPV - Cervical, anogenital, head and neck, skin cancer • HTLV-1 - Adult
Leukemia • HIV ... NHL, Hodgkin's lymphoma ... , Burkitt's lymphoma ... Associations #Cancers #oncology ... #differential #
Anaplastic large cell lymphoma, ALK+ Clinical • First 3 decades of life, M>F • Often nodal +
Anaplastic large ... cell lymphoma, ... variant can have leukemic ... advanced stage + B symptoms ... #largecell #lymphoma
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... pattern of spread, B symptoms ... ~10% - B-Cell ... Treated Like Acute Leukemias ... Diagnosis #NonHodgkin #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... accounts for 10% of all ... ingestion • B symptoms ... Immunohistochemical studies (to differentiate ... classification #hematology #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs and Symptoms ... general feeling of ill ... development of skin symptoms ... (malignancy), lymphoma ... #dermatology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Causes • Anemia • Aplastic ... Leukemia • Idiopathic ... blood count with differential ... diagnosis #hematology #oncology
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