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diagnosis hematology lymphoma management algorithm chronic classification cll lymphocytic alkpos anaplastic anemia associations cancers causes comparison diffuse disorders erythematosus hemeonc
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- B symptoms ... involved) • No leukemic ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Lymphadenopathy - Differential ... Pancytopenia, WBC differential ... Biopsy • Non-Hodgkin's ... Biopsy • Hodgkin's ... Causes #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... with no early symptoms ... Pure red cell aplasia ... , Hodgkin’s lymphoma ... diagnosis #workup #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... Overview Hodgkin's ... ingestion • B symptoms ... Immunohistochemical studies (to differentiate ... classification #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... • Age: 60-80 Clonal ... #Hematology #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... virus (EBV) • Leukemia ... • Improve the symptoms ... #Anemia #oncology
Infection-Related Cancers Viruses: • HPV - Cervical, anogenital, head and neck, skin cancer • HTLV-1 - Adult
- Adult T-cell Leukemia ... • EBV - NHL, Hodgkin's ... Associations #Cancers #oncology ... #differential #
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... cytometry → >500/uL clonal ... Constitutional symptoms ... #oncology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm Hodgkin ... Depletion Non-Hodgkin ... pattern of spread, B symptoms ... Treated Like Acute Leukemias
Anaplastic large cell lymphoma, ALK+ Clinical • First 3 decades of life, M>F • Often nodal +
Anaplastic large ... variant can have leukemic ... advanced stage + B symptoms ... around vessels • Hodgkin-like ... lauraebrown #Anaplastic
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