19 results
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Diagnosis Algorithm ... • Neoplastic (Leukemia ... , Lymphoma, Metastatic ... #Diagnosis #Algorithm ... Causes #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Diagnosis Algorithm ... Non-Hodgkin's Lymphoma ... • Hodgkin's Lymphoma ... #Diagnosis #Algorithm ... Causes #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Age: 60-80 Clonal ... and secondary lymphoid ... Small lymphocytic lymphoma ... of large cell lymphoma ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... Pure red cell aplasia ... #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
involved) • No leukemic ... involvement Differential ... Diagnosis of B-Symptoms ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV 
• EBV 
• CMV 
• HBV 
• Dengue 
• Rubella
Differential Diagnosis ... Malignancy • Lymphoma ... • Leukemia • ... #Diagnosis #Causes ... #Algorithm #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... cytometry → >500/uL clonal ... to large cell lymphoma ... #oncology #hematology ... #hemeonc #diagnosis
Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
- Adult T-cell Leukemia ... , Burkitt's lymphoma ... Associations #Cancers #oncology ... #differential # ... diagnosis #table
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... virus (EBV) • Leukemia ... • Improve the symptoms ... #Anemia #oncology ... #hematology #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Diagnosis Algorithm ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... #NonHodgkin #differential