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diagnosis hematology algorithm causes chronic classification cll diffuse hodgkins lad lymphocytic management comparison disorders focal generalized hemeonc localized lymphomas lymphoproliferative
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
- Differential ... • Neoplastic (Leukemia ... , Lymphoma, Metastatic ... #LAD #Differential ... Causes #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse Lymphadenopathy ... Non-Hodgkin's Lymphoma ... • Hodgkin's Lymphoma ... #Diffuse #Lymphadenopathy ... Causes #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Age: 60-80 Clonal ... and secondary lymphoid ... Small lymphocytic lymphoma ... of large cell lymphoma ... #Oncology #Diagnosis
Differential Diagnosis for Generalized Lymphadenopathy Viral • HIV • EBV • CMV • HBV • Dengue • Rubella
Differential Diagnosis ... Malignancy • Lymphoma ... • Leukemia • ... #Differential # ... Causes #Algorithm #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... Pure red cell aplasia ... diagnosis #workup #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
cytometry → >500/uL clonal ... ) Asymptomatic lymphadenopathy ... to large cell lymphoma ... Symptomatic massive lymphadenopathy ... #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involved) • No leukemic ... , lymphadenopathy ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... (NHL) ~60% - lymphadenopathy ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... Diagnosis #NonHodgkin #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... Presentation: • Lymphadenopathy ... ingestion • B symptoms ... Immunohistochemical studies (to differentiate ... classification #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Causes • Anemia • Aplastic ... • Hairy Cell Leukemia ... blood count with differential ... diagnosis #hematology #oncology
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