12 results
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... ) Diagnosis - Clonal ... • >60% plasma clonal ... Myeloma #Diagnosis #Management ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
cytometry → >500/uL clonal ... Splenomegaly 5) Symptoms ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... hemeonc #diagnosis #management
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
regimen Signs/Symptoms ... adenopathy, B symptoms ... viral load, signs/symptoms ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... • Age: 60-80 Clonal ... Leukemia #Hematology #Oncology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Hyperreflexia, Clonus ... defect SIGNS/SYMPTOMS ... Signs and symptoms ... /or cerebellar symptoms ... sclerosis #diagnosis #management
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
constitutional symptoms ... type) < 3 g/dL • Clonal ... proliferative disorder • Clonal ... hematology #diagnosis #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Jaw Jerk reflex, Clonus ... fasciculations Common Symptoms ... neurology #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• Improve the symptoms ... Aplastic #Anemia #oncology ... hematology #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... classification #hematology #oncology ... #management