22 results
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... and Howell Jolly ... bodies (nuclear ... HowellJolly #Body #Bodies
Common RBC Inclusions and Associations
 • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia
 • Heinz
Associations • Howell Jolly ... Severe hemolytic anemia ... • Heinz Bodies ... Sideroblastic anemia ... , Hemolytic anemia
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
bodies. ... These bodies represent ... Howell-Jolly bodies ... in sickle cell anemia ... . pernicious anemia
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... hyperplasia of bone ... breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Bite cells, Heinz bodies ... → Sickle Cell anemia ... Differential #Diagnosis #Algorithm
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Diagnostic Algorithm ... Iron deficiency anemia ... deficiency - Probable bone ... Underproduction #Algorithm
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... Low in bone marrow ... suggests appropriate bone ... Algorithm by Dr.
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... disease • Heinz bodies ... ARUPLabs #Hemolytic #Anemia ... Differential #Diagnosis #Algorithm
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... Flow cytometry, Bone ... Alcoholism Bone ... Acquired Aplastic Anemia ... Differential #Diagnosis #Algorithm
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... • Pernicious anemia