6 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammation of the bones ... Rule out other causes ... -1 inhibitors, IL ... inhibitors, and IL ... Rheumatology #diagnosis #management
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Myasthenic Crisis Checklist ... HFNC or BiPAP if mild-moderate ... to avoid (main ones ... MyastheniaGravis #Checklist ... #Management #CriticalCare
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... ., IFN-γ, TNF, IL ... Hemophagocytosis in bone ... Approach • Initial management
Efforts to standardize the approach to trauma have led to an algorithmic, thoughtless approach to trauma
have led to an algorithmic ... and delays CT in ill ... witnessed many cases ... #Management #Trauma ... BigTrauma #BeforeCT #Checklist
Orthopedic Splints, Casts, Plasters, Traction and Frames
Upper Limb and Spine 
 • DUNLOP TRACTION: Used in
flexor muscle and ill-development ... Used acutely in management ... treatment of fractured bones ... • ROBERT JONES ... #Orthopedics #management