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diagnosis differential hepatology management alkaline clinical hemophagocytic hlh lymphohistiocytosis phosphatase radiology rheumatology syndrome amyloid amyloidosis anatomy anemia checklist dermatology elevation
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms
Hand X-Ray Anatomy and Interpretation Checklist 1. Soft tissues - Look carefully at the soft tissue over
the bones for any ... Bones - All the ... bones of the hand ... in between the bones ... to the carpal bones
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Venoocclusive disease ... : Bone, first trimester ... differential #diagnosis #algorithm
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... inflammation of the bones ... • Bone and joint ... Rule out other causes ... osteoarticular and skin disease
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis Algorithm ... • Cushing's Disease ... Chemotherapy • Bone ... Celiac, IBD) • ... endocrinology #causes
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease ... fragmentation and mild ... bone marrow edema ... DOES NOT OSD in all ... marrow edema and bony
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Griscelli, Purtilo (XLP ... • Autoimmune diseases
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Ankylosing spondylitis, IBD ... the extent of disease ... muscle wasting Bone ... -1 & IL-6 → AA Protein ... hypoadrenalism • Nausea
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
loss of muscle, bone ... depletion in acutely ill ... prolonged rest can cause ... lying down and can cause ... Anemia of renal disease
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