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diagnosis differential management hematology msk orthopedics anemia clinical hepatology treatment infectiousdiseases pathophysiology radiology syndrome alkaline alp checklist classification criticalcare endocrinology
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
of Bone • Characterized ... and formation of bone ... • Caused by ( ... more (polystotic) bones ... pelvis, and long bones
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long bones ... BrighamChiefs #Bone ... Pain #SickleCell #Disease
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... excessive bone ... MSK • Deformed bones ... Lytic lesions make bones ... of middle ear bones
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Flow cytometry, Bone ... Alcoholism Bone ... • Congenital bone ... Metastatic Disease
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... hyperplasia of bone ... #Differential #Causes ... #Workup #Hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
Hand X-Ray Anatomy and Interpretation Checklist 1. Soft tissues - Look carefully at the soft tissue over
tissue over all the bones ... Bones - All the ... bones of the hand ... in between the bones ... to the carpal bones
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Underproduction Diagnostic Algorithm ... chronic kidney disease ... deficiency - Probable bone ... Underproduction #Algorithm ... #differential #workup
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Flow cytometry, Bone ... Alcoholism Bone ... • Congenital bone ... Metastatic Disease
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