27 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long bones ... BrighamChiefs #Bone ... #differential #
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential ... Flow cytometry, Bone ... Alcoholism Bone ... • Congenital bone ... Metastatic Disease
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... hyperplasia of bone ... #Differential # ... Causes #Workup #
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - Differential ... Diagnosis Algorithm ... Granulomatous Disease ... Miscellaneous - Bone ... #causes #endocrinology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential ... Flow cytometry, Bone ... Alcoholism Bone ... • Congenital bone ... Metastatic Disease
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Underproduction Diagnostic Algorithm ... chronic kidney disease ... deficiency - Probable bone ... hematology #diagnosis #differential ... #workup
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Fragility Fractures - Differential ... Diagnosis Algorithm ... Tumours - See Bone ... • Bone Marrow ... #Orthopedics #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Chronic diarrhea / IBD ... Pancreatitis - Hungry bones ... Hypomagnesemia #Differential ... Classification #Causes ... #Workup #hypomg
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... PT, aPTT(liver disease ... candidate) - Bone ... #Workup #hematology