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Mechanism of malignancy-associated hypercalcemia. Abbreviations: 1,25(OH)2D, 1,25-dihydroxyvitamin D; NHL, non-Hodgkin lymphoma; PTH, parathyroid hormone; PTHrP, PTH-related
Abbreviations: 1,25(OH ... non-Hodgkin lymphoma; PTH ... hormone; PTHrP, PTH-related
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH LOW PTH - Hypoparathyroid - Congenital (Pediatric)
- Low and High PTH ... LOW PTH - Hypoparathyroid ... Hypomagnesemia HIGH PTH ... - 25-OH D very ... anti-convulsants) - 25-OH
Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. Vitamin D
vitamin D and PTH ... Both 25(OH)D and ... 1,25(OH)2D are ... PTH acts to increase ... #Homeostasis #PTH
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Algorithm Elevated PTH ... Hypercalcemia Low PTH ... Calcitriol (1,25 OH
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Evaluation 1) Clinical ... 2) PTH - Frankly ... PTHrp • 25 OH ... VitD & 1,25 OH
Hypocalcemia - Differential Diagnosis Algorithm • Low Serum Mg: GI losses, Renal losses, Alcoholism, Malnutrition, Drug-Induced
Drug-Induced • Intact PTH ... Pseudohypoparathyroidism (PTH ... resistance) • Intact PTH ... • Low Serum 25-OH
Tinea Versicolor (Pityriasis versicolor) NOT a dermatophyte infection Caused by saprophytic, lipid-dependent yeasts Clinical •
lipid-dependent yeasts Clinical ... Potassium hydroxide (KOH
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Malignancy • PTH-Related ... Conversion of 25-OH ... D3 to 1,25-(OH)
Lancisi's Sign (Tricuspid Regurgitation) in a patient with Atrial Fibrillation If you went to med school before
:) One clue: Pt ... finger on the pts ... Pt has permanent ... Fibrillation #Neck #JVP #Clinical ... #Video #AFib #PhysicalExam
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 Kussmaul's Sign and Friedreich's Sign on Neck Examination A middle-aged M with unknown PMH presents with dyspnea.
M with unknown PMH ... demonstrated in the video ... Pt was amazed - ... #PhysicalExam #Clinical ... #Video #Cardiology
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