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Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Vasospastic (Prinzmetal) Angina Definition / Epidemiology: • Rest angina attributed to coronary artery vasospasm. • Patients often
younger than other ACS ... Pathophysiology: ... changes on tele/ECG ... tests in cath lab Treatment ... Prinzmetal #Angina #cardiology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... function test, ANA (e.g ... not required in all ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... permeability Diagnosis ... Lumbar Puncture, EEG ... Treatment: ... #cerebritis #diagnosis
Myocarditis 5 Principles of Myocarditis: 1. Build clinical suspicion 2. Decide on EMBx 3. Manage acute cardiac injury 4. Manage chronic
Pericarditis, Tamponade EKG ... Low voltage Treatment ... agent, steroids, AC ... #Myocarditis #diagnosis ... #management #cardiology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
inflammation (eg ... been reported (eg ... of Hepatitis (eg ... Histology Findings (eg ... regarding need for treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... #management #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Person Syndrome Pathophysiology ... unit activity on EMG ... of diazepam • EMG ... antibody that works ... TPO, TTG, etc EMG
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
cardiomyopathy (e.g ... hemodynamics (e.g ... LVEF recovery (e.g ... teratogenic GDMT meds (e.g ... #treatment
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