17 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... #diagnosis #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Differential Diaqnoses ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... transformation into AML ... • Treatment algorithms ... #Management #Summary ... #treatment #hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
HIT laboratory tests ... and to adjust treatment ... #Diagnosis #Management ... #Hematology #HIT ... Thrombocytopenia #Algorithm
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • Fever ... Tuberculosis Diagnosis ... Tuberculosis Treatment ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • Fever ... Tuberculosis Diagnosis ... Tuberculosis Treatment ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Liver function tests ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
respiratory symptoms • Fever ... symptoms • Rheumatologic ... infection • Cough, fever ... • Isolated fever ... #Management #Infections
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Lymphadenitis, pulmonary ... - Pneumonitis (fever ... leukoencephalopathy (PML ... Fever, chills, lack ... #Management