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endocrinology dm2 titration ckd management prescribing renal binder ckd3 ckd4 clinical dose dpp4 fingernails hands hyperkalemia indications inhibitors initiation kbinder
Mechanism of Action for Common Diabetes Medications • SGLT2i (Dapagliflozin) • TZD (Pioglitazone) • Biguanides (Metformin)
Mechanism of Action ... for Common Diabetes ... • Biguanides (Metformin ... • Biguanides (Metformin ... #Medications #pharmacology
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or
Metformin Treatment ... Patients With Type 2 Diabetes ... 3A, 3B, or 4 Diabetes ... #CKD3 #CKD4 #Dosing ... #Pharmacology #
Algorithm for Metformin Prescribing and Dosing in CKD Dose Initiation - Immediate release: • Initial 500 mg
Algorithm for Metformin ... Prescribing and Dosing ... #Prescribing #Dosing ... #CKD #pharmacology ... #algorithm #diabetes
Metformin Current Renal Dose Adjustments due to Risk of Lactic Acidosis > 60 No adjustment 45-60
Metformin Current ... already taking metformin ... #Renal #Dosing ... #Dose #Pharmacology ... #Diabetes
Metformin: Biguanide Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
treatment of type 2 diabetes ... to it's triple mechanism ... 2000 mg/day) and using ... #Pharmacology # ... Mechanism #Diabetes
Metformin - First Line Treatment for Diabetes Type 2 • Start with initial dose of 500 mg
Metformin - First ... Treatment for Diabetes ... form and consider using ... Indications #Titration #Pharmacology ... #Diabetes #DM2
Metformin in Diabetic Kidney Disease Immediate release: • Initial 500 mg or 850 mg once daily •
Metformin in Diabetic ... eGFR < 30: Stop metformin ... annually if on metformin ... #CKD #pharmacology ... #algorithm #management
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... Various debated mechanisms ... #Pharmacology # ... Summary #DM2 #diabetes
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... This mechanism helps ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Management #Diabetes
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
(Patiromer) MECHANISM ... oral suspension DOSING ... with CKD, HF, or diabetes ... #Hyperkalemia #Pharmacology
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