8 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... DIC • Severe Liver ... #Disseminated #Intravascular
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... In liver, 80% of ... Chemistry #Tests #Laboratory ... Bilirubin #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Syndrome, Ischemic Liver ... cardiac valves (septic ... Hyperhomocysteinemia - Heparin-induced ... - Disseminated intravascular ... Venous #Arterial #pathophysiology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Diseases • Septic ... more time for the laboratory ... profile, including liver ... function tests (LFTs ... #laboratory #workup
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
with motion • Lots ... in Rheumatoid arthritis ... Stiffness is short-lived ... JointPain #Diagnosis #pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... Extrapulmonary: ankle arthritis ... heart (2-5%), liver ... (pain/abnormal LFT
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Mississippi and Ohio River ... Aspergillosis Pathophysiology ... • Meningitis, septic ... arthritis, and ... anidulafungin) • Intravascular
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
thrombocytopenia syndrome (SFTS ... syndrome - IGG4 - Hepatic ... cell lymphoma - Intravascular ... cell lymphoma Pathophysiology