26 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... • NAFLD • Cirrhosis ... ) • Non-hepatic ... #Differential #
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... Disease (Cirrhosis ... Esophageal Varices • Hepatic ... #Cirrhosis #Complications ... #diagnosis #management
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... more specific for hepatic ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Clues to non-cirrhotic ... sarcoidosis) • Liver ... metastasis • Fatty liver ... #Hypertension #Differential
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... failure - 3-5% Cirrhosis ... Disease, Fulminant Hepatic
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
or secondary to cirrhosis ... 3) Sinusoidal: Cirrhosis ... , Polycystic liver ... disease 5) Post-hepatic ... portalhypertension #phtn #differential
Portal Hypertension Classification by site of vascular obstruction
1) Post-hepatic Post-sinusoidal: Budd-Chiari syndrome
2) Intrahepatic Post-sinusoidal: Veno-occlusive disease
3)
obstruction 1) Post-hepatic ... 3) Sinusoidal: Cirrhosis ... , Polycystic liver ... or secondary to cirrhosis ... gastroenterology #diagnosis #differential
Approach to the Hospitalized Patient with Cirrhosis
1) Recognize and Manage Decompensation
 • Ascites
 • Variceal Bleeding
Hospitalized Patient with Cirrhosis ... Variceal Bleeding • Hepatic ... Portosystemic Shunt • Liver ... DeanEhrlich_MD #inpatient #Cirrhosis ... diagnosis #treatment #management
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... replaced by non-hepatic ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... transaminitis #LFTs
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Patterns #Liver ... Injury #hepatology #LFTs ... transaminitis #differential