28 results
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... (e.g. heparin, LMWH ... #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban ... #Fondaparinux #NOAC
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #INR #heparin #LMWH ... #NOAC #warfarin ... rivaroxaban #Xarelto #apixaban ... #Eliquis #dabigatran
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Kcentra) - Heparin/LMWH ... Protamine sulfate - Dabigatran ... (Praxbind) - Apixaban ... #noac #pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... and bridging for VTE ... #DOAC #Bridging ... Anticoagulation #Dabigatran ... #Apixaban #Rivaroxaban
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Rivaroxaban • Apixaban ... • Dabigatran ... #NOAC #DOAC #Pharmacology ... #Direct #Oral #AntiCoagulant
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Switching Between Anticoagulants ... and DOACs VKA, Dabigatran ... , Rivaroxaban, Apixaban ... Edoxaban, Betrixaban, DOAC ... , Parenteral anticoagulant
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Renal Dosing: Apixaban ... patients 5mg bid Dabigatran ... #Pharmacology #Apixaban ... #Rivaroxaban #Dabigatran ... #Edoxaban #NOAC
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Pharmacology Warfarin - Dabigatran ... Rivaroxaban - Apixaban ... #Pharmacology #NOAC ... comparison #table #dabigatran ... #rivaroxaban #apixaban
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Clearance of Oral Anticoagulant ... Hepatic, 0% Renal Apixaban ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
Choice of anticoagulant ... - Rivaroxaban; apixaban ... Gl bleed - VKA, apixaban ... #anticoagulant ... #decisionaid #vte