22 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Anti-Coagulants • Rivaroxaban ... • Apixaban • Dabigatran ... #NOAC #DOAC #Pharmacology ... Prescribing #hematology #management
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC ... - Rivaroxaban - ... h) #Warfarin #DOAC ... #Pharmacology #NOAC ... #rivaroxaban #apixaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Kcentra) - Heparin/LMWH ... Protamine sulfate - Dabigatran ... Edoxaban (Lixiana), Rivaroxaban ... anticoagulation #doac ... #noac #pharmacology
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
#INR #heparin #LMWH ... #NOAC #warfarin ... #coumadin #rivaroxaban ... apixaban #Eliquis #dabigatran ... #Pradaxa #management
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Hepatic, 25% Renal Dabigatran ... Hepatic, 50% Renal Rivaroxaban ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... VKA, Dabigatran ... , Rivaroxaban, Apixaban ... Edoxaban, Betrixaban, DOAC ... Anticoagulants #DOACs
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... patients 5mg bid Dabigatran ... @Bloodman #DOAC ... #Dabigatran #Edoxaban ... #NOAC
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Weight Heparin (LMWH ... inhibitors - Apixaban, rivaroxaban ... ) inhibitors - Dabigatran ... #medications #doac ... comparison #table #management
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... , Edoxaban, Rivaroxaban ... DeLoughery @Bloodman #DOAC
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... Apixaban, Edoxaban or Rivaroxaban ... modified factor Xa • Dabigatran ... not available #DOAC ... #Reversal #NOAC