25 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Anti-Coagulants • Rivaroxaban ... • Apixaban • Dabigatran ... #NOAC #DOAC #Pharmacology ... Prescribing #hematology #management
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC ... - Rivaroxaban - ... h) #Warfarin #DOAC ... #Pharmacology #NOAC ... #rivaroxaban #apixaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Kcentra) - Heparin/LMWH ... Protamine sulfate - Dabigatran ... Edoxaban (Lixiana), Rivaroxaban ... anticoagulation #doac ... #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Clearance of Oral ... Hepatic, 25% Renal Dabigatran ... Hepatic, 50% Renal Rivaroxaban ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
#INR #heparin #LMWH ... #NOAC #warfarin ... #coumadin #rivaroxaban ... apixaban #Eliquis #dabigatran ... #Pradaxa #management
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... not available #DOAC ... #Reversal #NOAC ... #Oral #anticoagulant ... #hematology #management
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
(e.g. heparin, LMWH ... weight heparin (LMWH ... - Rivaroxaban ... #UFH #DOAC #Dabigatran ... #Fondaparinux #NOAC
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Management Cheat ... Warfarin, Apixaban, Dabigatran ... , Rivaroxaban ... Anticoagulant #DOAC
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... VKA, Dabigatran ... , Rivaroxaban, Apixaban ... Edoxaban, Betrixaban, DOAC ... Anticoagulants #DOACs
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... patients 5mg bid Dabigatran ... @Bloodman #DOAC ... #Dabigatran #Edoxaban ... #NOAC