12 results
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Agents - Warfarin ... Kcentra) - Heparin/LMWH ... Protamine sulfate - Dabigatran ... Edoxaban (Lixiana), Rivaroxaban ... #noac #pharmacology
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
#INR #heparin #LMWH ... #NOAC #warfarin ... #coumadin #rivaroxaban ... apixaban #Eliquis #dabigatran ... Pradaxa #management #pharmacology
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Management Cheat Sheet: Warfarin ... , Apixaban, Dabigatran ... , Rivaroxaban ... Adjustrnent - Reversal ... Management #Table #Pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... Anticoagulation #Dabigatran ... #Apixaban #Rivaroxaban ... #Loading #DVT #Pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Clearance of Oral ... Anticoagulant Agents Warfarin ... Hepatic, 25% Renal Dabigatran ... Hepatic, 50% Renal Rivaroxaban ... #Pharmacology #
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... anticoagulant (e.g. warfarin ... #Pharmacology #Pathophysiology ... #UFH #DOAC #Dabigatran ... #Fondaparinux #NOAC
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
• Once a day oral ... therapy - Rivaroxaban ... UFH • Need of reversal ... #decisionaid #vte ... anticoagulation #pharmacology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Weight Heparin (LMWH ... Enoxaparin - Warfarin ... inhibitors - Apixaban, rivaroxaban ... ) inhibitors - Dabigatran ... anticoagulation #pharmacology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... , edoxaban and rivaroxaban ... anticoagulant; LMWH ... #DOAC #VTE #Malignancy ... #Cancer #Algorithm
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... Apixaban, Edoxaban or Rivaroxaban ... modified factor Xa • Dabigatran ... #Reversal #NOAC ... #Oral #anticoagulant