76 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... activate macrophages ... , mast cells or ... Stevens-Johnson Syndrome ... Allergy #Immunology #pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
5-a-reductase activity ... testicular Leydig cells ... NSAlDs -> Decr COX activity ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... = funny-shaped cells ... diagnosed annually in US ... Myelodysplastic #Syndrome
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... and activate them ... neutralizing them - Activate ... Complement: Abs activate ... Humoral #Immunity #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... Natural Killer Cells ... cytotoxic cell activity ... #Inflammation #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... of dopaminergic activity ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel Syndrome ... (IBS) - Management ... Secretagogues → activate ... intestinal epithelial cells ... Irritable #Bowel #Syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... : • Pathophysiology ... Lysis of tumor cells ... TLS #diagnosis #management
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... the mastoid air cells ... of fluid &/or pus ... accumulation of pus ... #Mastoiditis #pathophysiology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Pathogenesis and clinical ... Risk of Refeeding Syndrome ... PO4 and Mg into cells ... #diagnosis #pathophysiology