11 results
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
anticoagulants (DOACs ... filtration rate; DOAC ... anticoagulant; LMWH ... body mass index; VTE ... #DOAC #VTE #Malignancy
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE ... in Malignancy ... risk of recurrent VTE ... DOAC, direct oral ... #DOAC #VTE #Malignancy
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... . heparin, LMWH, ... anticoagulant (e.g ... #UFH #DOAC #Dabigatran ... #Fondaparinux #NOAC
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
pulmonary embolism • Malignancy ... - LMWH • To avoid ... coagulopathy - LMWH ... • Pregnancy - LMWH ... #decisionaid #vte
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g ... Medications - Heparin, LMWH ... , warfarin, DOACs ... (e.g. direct factor ... most common) - Malignancy
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
thromboembolism (VTE ... • Provoked (e.g ... trauma, active malignancy ... an established malignancy ... - Recurrent VTE
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
cardiomyopathy (e.g ... Avoid Warfarin and DOAC ... hemodynamics (e.g ... LVEF recovery (e.g ... Serial TTE and close
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Non-Infectious (NTBE): • Malignancy ... cultures • 2D Echo TTE ... • TTE nondiagnostic ... ↑ ESR, CRP • EKG
#ICUCard
RENAL
GFR
90-131
mL/min
((140-age)*Wt)/(72*Cr)
Glomerular Filtration Rate (Cockcroft)
CI Cr
90-131
mL/min
(CrU * volume)/CrS
Creatinine Clearance
FENa
0.0-1.0
%
((U/P Na)/(U/P Cr))*100
Fractional Excretion of Na+
Na req
mEq
(125-Na)*0.6*Wt
Required Sodium
FE Urea
275-295 mOsm/kg ... 0.0-10.0 mOsm/kg ... PEEP < 5 cm H20 VT ... , Shunt < 20% VD ... /VT < 0.6, Patient
Perform computations online at:
ScyMed.com
6th ED
ICU-card
«ICU, Formulas & Drugs»
HEMODYNAMIC PATTERNS
Condition
SAP
CVP

PAP PCWP

CO C(a-v)02 PVR

SVR
Hypovolemic shock
↓
↓
↓
↓
↓
↑
↑
↑
Cardiogenic shock
↓
1
↑
1

1
↑

Septic shock
↓
↓
↓
↓
↑
↓
↓
↓
Cardiac Tamponade
.
↑
↑
1
↓

→
↑
RV
LCWI 3.4-4.2 kg ... PULMONARY RR VT ... Tidal Volume VE ... Minute Ventilation VD ... 80-300 mL (VT