10 results
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
and first-level screening ... test - High sensitivity ... and specificity ... #Testing #Laboratory ... #Workup #Table
Sensitivity is the proportion of truly diseased persons in the screened population who are identified as
by the screening ... Specificity is the ... scores on the screening ... #Specificity #PositivePredictiveValue ... #Calculation #Table
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
- Laboratory Testing ... normal but poor sensitivity ... Ferritin-best non-invasive test ... #Laboratory #Testing ... #Comparison #Table
Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based tests:
 • FIT: 79% sensitivity, 94% specificity for CRC
Colorectal Cancer Screening ... tests: • FIT: ... Cancer #colon #Screening ... #table #management ... gastroenterology #CRC #Testing
ACA Colorectal Cancer Screening Guidelines

When to Screen?
When to Stop?
Family History

Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based
Colorectal Cancer Screening ... Colorectal Cancer Screening ... Cancer #colon #Screening ... #comparison #table ... gastroenterology #CRC #Testing
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
has higher specificity ... but lower sensitivity ... more time for the laboratory ... Screening Tests ... Screening Tests
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Insufficiency - Algorithm ... Step 1) Screening ... have almost 100% specificity ... for AI (but low sensitivity ... require Cosyntropin testing
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Sensitivity (rule ... out – screening ... Specificity (rule ... FN) Higher specificity ... PPV Higher sensitivity
Antibiotic Susceptibility Testing Methods
1) Kirby Bauer Disk Diffusion: disks impregnanted w/ Abx → circular gradient →
Gradient diffusion (E test ... concentrations + algorithms ... MIC Infectious Diseases ... #Antibiotic #Sensitivity ... #laboratory #microbiology
Celiac Disease - Diagnosis Algorithm
IgA TTG has high sensitivity and specificity of ~ 98% and is
Celiac Disease - ... Diagnosis Algorithm ... IgA TTG has high sensitivity ... and specificity ... pts need further testing