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diagnosis differential hematology hemolytic ascorbicacid bronchiectasis cardiology celiac disease erythematosus extravascular gastroenterology gluten hemolysis hypokalemia immunecompromised immunocompromised intravascular lupus management
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... • PK deficiency ... perfringens - Complement-Mediated ... immune-complex hemolytic anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... bartonella (oroya fever ... ARUPLabs #Hemolytic #Anemia ... workup #hematology #testing
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... DAT (-) → G6PD Deficiency ... Recent travel/Fevers ... Differential #Diagnosis #Algorithm ... #causes
Celiac Disease Testing Algorithm INDICATIONS FOR TESTING: Nonspecific symptoms (iron-deficiency anemia, failure to thrive, fever, skin
Algorithm INDICATIONS ... symptoms (iron-deficiency ... anemia, failure ... to thrive, fever ... #Algorithm #diagnosis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... Ill temper • Fever ... , anemia, edema, ... Loss of teeth Anemia ... , or any other cause
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Periodontal Disease Complement ... Deficiency • ... Infection #Fever ... #Causes #Hematology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Chronic inflammation causes ... run-down or tired • Fevers ... Most Common Causes ... Bronchoscopy Laboratory ... α1-antitrypsin deficiency
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... ) and laboratory ... anti-Smith Ab, low complements ... disease • Prolidase deficiency ... lymphopenia, low PLT • Anemia
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
ECG • Limited laboratory ... testing Heart ... • Bradycardia caused ... Electrolyte imbalance • Fever ... Hyperthyroidism • Anemia
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... confirmed via genetic testing ... continued in most cases ... ; interpretation ... dependent upon local laboratory
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