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differential rheumatology allergy causes erythematosus hypersensitivity nephrology reactions syndrome acidosis rheumatoid signs sle symptoms table allergic aniongap comparison criteria cryoglobulinemia
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... lupus • Arthritis ... least 2 joints • Neurologic ... #diagnosis #rheumatology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
complexes • Ex: Systemic ... Lupus Erythematosus ... , Reactive Arthritis ... #Classification ... #Diagnosis #Definitions
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... glomerulonephritis, rheumatoid arthritis ... , and systemic lupus ... #Classification ... Pathophysiology #Allergy #Diagnosis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
days - Examples: Acute ... Examples: Rheumatoid arthritis ... glomerulonephritis, Systemic ... lupus erythematosus ... allergy #table #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Labs/Diagnosis: ... disorder (e.g. systemic ... lupus erythematosus ... #types #classification
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... lupus erythematosus ... , Rheumatoid arthritis ... , Systemic sclerosis ... #nephrology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... : • Acute cutaneous ... (ACLE) • Erythematous ... Kikuchi disease • Type-I
Cutaneous Lupus Erythematosus • Acute Cutaneous Lupus (ACLE) • Neutrophilic Dermatoses • Vascular Lesions •
Erythematosus • Acute ... (ACLE) • Neutrophilic ... Erythematosus #diagnosis ... #types #venn #rheumatology ... #classification
Rheumatoid Arthritis - 2020 ACR-EULAR Classification ≥ 6 of 10 points = definite RA Joint Involvement:
Rheumatoid Arthritis ... - 2020 ACR-EULAR ... Classification ... Ab - 3 points Acute ... #diagnosis #EULAR
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Renal failure (acute ... Proximal RTA (type ... ACE-Is and ARBs ... #differential #diagnosis ... #causes #nephrology
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