16 results
diagnosis differential algorithm metabolic causes hypokalemia pathophysiology syndrome chloride low medications urine acidosis action aniongap classes conversion diuresis excretion hypochloremia
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
action on the nephron ... Metolazone) 5) Potassium-sparing ... triamterene) #nephron ... #diuretics #pharmacology ... #nephrology #medications
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... intake, Diuretics ... -: Diuretics, Bartter ... Syndrome, Gitelman ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... intake, Diuretics ... -: Diuretics, Bartter ... Syndrome, Gitelman ... Diagnosis #Algorithm #Nephrology
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... Piretanide Potassium ... loss through the nephron ... nephrology #conversion
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... distal tubule. ↑ Nacl ... delivery to distal nephron ... Hypokalemia Metabolic alkalosis ... Pathophysiology #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
loop or thiazide diuretics ... pressure: Active diuretic ... Bartter syndrome, Gitelman ... of sodium and potassium ... urine #Algorithm #nephrology
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypertensive: • High Al ... >20 mEq/24 h - Diuretics ... Bartter's syndrome, Gitelman's ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Thiazide or loop diuretics ... after renal tubule diuretic ... furosemide-like lesion) • Gitelman ... other • Severe potassium ... Diagnosis #Causes #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
with thiazide diuretic ... Hypokalemia (renal potassium ... Surreptitious diuretic ... Supplement: • Potassium ... Syndrome #diagnosis #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... - Metabolic Alkalosis ... : Emesis, Diuretics ... Bartter syndrome, Gitelman ... #nephrology #low
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