4 results
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... • Inhibit Na+ Cl ... loss through the nephron ... nephrology #conversion
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
gene that encodes thiazide-sensitive ... distal tubule. ↑ Nacl ... delivery to distal nephron ... → Hypokalemia Metabolic ... Pathophysiology #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
use of loop or thiazide ... diuretics ... pressure: Active diuretic ... Bartter syndrome, Gitelman ... urine #Algorithm #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... resistance • Metabolic ... Inhibitors of Na+K+2Cl ... +CI- Symport - Thiazide ... #Nephrology #Pharmacology