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management signs symptoms erythematosus lupus sle systemic disease antimda5 antimda5dm arteritis autoantibodies autoimmune behcet bilateral blines bone causes checklist crisis
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Generally affects long ... predispose to other orthopedic ... Osteomyelitis / Septic Arthritis ... #diagnosis #causes ... #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Myositis 4% - Lung ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... effusion, Restrictive lung ... of hip (rare), Arthritis ... erythematosus #signs ... #rheumatology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... mass and NO prior signs ... Differential diagnosis ... #mri #clinical ... #msk #rheumatology
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
Differential Bilat ... partially seen shred sign ... NOT definitively diagnose ... #POCUS #clinical ... #ultrasound
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 Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... knees, shoulders Signs ... narrowing) • Ultrasound ... Diagnosis: CLINICAL ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... Behcet disease) Differential ... #management #signs ... #symptoms #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... very remarkable w/differential ... them, but urgent rheumatology ... GCA #Temporal #Signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... anti-NXP2 Abs Lung ... • Arthralgia/arthritis ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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