15 results
Carbon Monoxide Poisoning

Symptoms are non-specific:
 - Headache 90%
 - Nausea/vomiting 50%
 - Vertigo 50%
 - Altered
Monoxide Poisoning Symptoms ... affected (inc pets ... Outdoors improves symptoms ... Monoxide #Poisoning #Toxicology ... #diagnosis #management
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... dose dependent injury ... ongoing ↑ LFTs or symptoms ... #differential #Diagnosis ... gastroenterology #hepatology
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
frequently begins after injury ... • Systemic symptoms ... #Osteosarcoma #Diagnosis ... Features #Oncology #Peds
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
anaerobic metabolism Diagnosis ... and acute kidney injury ... also includes symptoms ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
caustic mucosal injury ... post-ingestion) - Symptom ... caustic bowel injury ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
Non-accidental Injury ... neurology, back pain Haematology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
- Symptoms of ... pattern of liver injury ... Diagnosis - If suspected ... , AIH diagnosis ... #Management #Hepatology
Clinical features of Liver Disease in Children

#Cirrhosis #LiverFailure #Signs #Symptoms #PhysicalExam #Findings #Diagnosis #Peds #Pediatrics #Hepatology

**
LiverFailure #Signs #Symptoms ... PhysicalExam #Findings #Diagnosis ... #Peds #Pediatrics ... #Hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
hemolysis or liver injury ... examination; nonspecific symptoms ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management