19 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... • Weakness: Starts ... Treatment: • Plasmapheresis ... #management #treatment
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - ... Differential Diagnosis ... • Turner Syndrome ... Panhypopituitarism Treatment ... #ShortStature #Differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... : • Pathophysiology ... unless worrisome EKG
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... and cauda equina TREATMENT ... #Syndrome #diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... hypertension and signs ... renal bruit or signs ... , and Guillain-Barre ... Workup #causes #Differential
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... hyperthermia crisis (late sign ... • Serotonin syndrome ... Anticholinergic syndrome ... #Hyperthermia #Differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... life-threatening Differential ... Serologic and EMG ... test - Cogan sign ... - Peek sign
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... • Lhermitte’s sign ... Multiple Sclerosis Treatment ... taper 3-7 days - Short ... management #neurology #treatment
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
cardiac syncope, e.g ... carotid sinus syndrome ... syncope (ruling out differential ... orthostatic vital sign ... The treatment strategy
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... initiation • Differential